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| usou7v |  Posté 14/11/2018 07:08
MYB（6q23）gene probe
◆Product Advantages
1.Fleetness: Tissue probe hybridization time: 2 hours. Cell probe hybridization time: 1 hour.
2.Accuracy: Less non-specific background staining (dyeing). Increase difficult samples detection rate.
3.Reproducibility: Different laboratories test results are highly reproducible.
◆Probe Description
MYB/CEP6 is a dual-color hybrid probe in which green dye directly labels the CEP6 probe, which specifically acts on chromosome 6 (D6Z1), while the red dye directly labels the MYB probe, which specifically acts on the probe. The MYB gene at the 6q23.2-23.3 region of the chromosomal region.
◆Clinical Significance
The 6q deletion abnormality is the fourth most common abnormality of B-CLL, about 10%, and the 6q deletion has a poor prognosis in various tumors including CLL; this probe can detect the small missing region of 2Mb which is not distinguishable by karyotype analysis.
◆Size Specifications
◆References
Urbankova H, et al. (2014) Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 158: 56-64.
Wang DM, et al. (2011) Leuk Lymphoma 52: 230-7.Fluorescence In-situ Hybridization Probes manufacturers
website:http://www.health-carebiotech.com/molecular-diagnostic-probe/fluorescence-in-situ-hybridization-probes/
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